http://www.enterpriseeuropeeast.org.uk/eox/assets/images/sitelook/een.gif Tue, 31 Jan 2012 00:00:01 GMT Technology collaboration - 12 EE 21B9 3NVH OFFER

An Estonian SME has developed competences in HRM (High Resolution Melting) based genetic and epigenetic analyzing to medical and research laboratories. The method is fast, sensitive and cost-effective, enabling to detect specific variations even with relatively low incidence. Technical Cooperation or Commercial Agreement with Technical Assistance is sought.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 EE 21B9 3NVH&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 EE 21B9 3NVH&EnquiryType=BBS Tue, 31 Jan 2012 00:00:02 GMT Technology collaboration - 12 LU 87GA 3NZZ REQUEST

A large US company is looking for proposals for validated in vivo models able to link inhibition of autotoxin (ATX) activity and decline of lysophosphatidic acid (LPA) levels to the reduction of clinically relevant biomarkers, preferably, but not limited to oncology, immune-mediated diseases, or fibrosis. They are interested in contract research, joint development license agreement.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 LU 87GA 3NZZ&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 LU 87GA 3NZZ&EnquiryType=BBS Fri, 27 Jan 2012 00:00:03 GMT Technology collaboration - 12 FI 30I0 3NZJ OFFER

A Finnish research group has identified and isolated previously unknown CD117+ adult vascular endothelial stem cells (VESCs), which could be used in cell-based therapies to restore tissue vascularization in ischemic situation such as atherosclerosis and coronary artery disease. These cells are also the true biological target for all existing and future anti-angiogenic therapies. The researchers are looking for biotech or pharmaceutical companies for R&D partnership and out-licensing.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 FI 30I0 3NZJ&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 FI 30I0 3NZJ&EnquiryType=BBS Fri, 27 Jan 2012 00:00:04 GMT Technology collaboration - 12 IL 80EP 3O1C REQUEST

An Israeli clinical stage biotechnology company is looking for a partner to collaborate on developing its lead compound, a short peptide antagonist of CD28, for treatment of immune related diseases. The company is seeking to collaborate with service providers, academic researchers and clinical investigators in the fields of drug development (preclinical and clinical) in the area of Cardiovascular Ischemia reperfusion injury and multiple myeloma.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 IL 80EP 3O1C&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 IL 80EP 3O1C&EnquiryType=BBS Wed, 25 Jan 2012 00:00:05 GMT Technology collaboration - 12 ES 27F4 3NXY OFFER

An Andalucian research group has developed and patented a technology for obtaining animal cell lines resistant to cytotoxic drugs that act by inhibiting the vacuolar ATPase. These cell lines may be the basis for restoring tissues and organs damaged by chemotherapy. Industrial partners interested in a patent license for the exploitation of the technology are sought.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 ES 27F4 3NXY&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 ES 27F4 3NXY&EnquiryType=BBS Mon, 23 Jan 2012 00:00:06 GMT Technology collaboration - 12 IT 56Z6 3NWE OFFER

A research group from North of Italy invented nanocomposite systems based on gold nanoparticles coated with creatine, an modified amino acid and human serum albumin able to cross the blood barrier in therapeutically relevant concentrations as potential drug for stroke to prevent oxygendeficiency induced neurodegeneration. These nanoparticles offer additionally the possibility of detection and tracking particle binding to the target such as protein aggregates. They look for licence agreements.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 IT 56Z6 3NWE&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 IT 56Z6 3NWE&EnquiryType=BBS Mon, 23 Jan 2012 00:00:07 GMT Technology collaboration - 12 IT 56Z6 3NWF OFFER

An Italian research group invented polymeric nanoparticles made of the non-toxic, FDA approved polycation, chitosan in combination with either an antibody or cytokines regulating the immune response of the body against tumor cells. Innovative aspects of the invention: chitosan binds proton and returns the acidic tumor pH to the normal tissue pH; antibody inhibits tumor protection; cytokines activate immune cascade; positive charge of chitosan attracts macrophages. Licence agreements sought.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 IT 56Z6 3NWF&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 IT 56Z6 3NWF&EnquiryType=BBS Fri, 20 Jan 2012 00:00:08 GMT Technology collaboration - 12 ES 28G2 3NVY OFFER

A Spanish public research organisation has developed a method to obtain magnetic nanoparticles with size between 5-30 nm made of a magnetite core covered by a bismuth shell. The nanoparticles, of high cristalinity and low size dispersion, can be employed for diagnose by RMN, MRI or TAC, as tumor markers or for therapeutic applications (drug carrier or heat source for treatment by magnetic hyperthermia). Partners interested in a patent license are being sought.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 ES 28G2 3NVY&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 ES 28G2 3NVY&EnquiryType=BBS Mon, 16 Jan 2012 00:00:09 GMT Technology collaboration - 11 BE 0213 3NLT OFFER

This Brussels-based company is a leader in the design, development and distribution of innovative products in the radiotherapy field. They offer the only patient positioning laser system on the market that allows a more precise imaging and treatment of patients, which can be used in scanner's room and in accelerator's room. The company looks for technical cooperation and for commercial agreement with technical assistance with different kinds of partners.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 BE 0213 3NLT&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 BE 0213 3NLT&EnquiryType=BBS Thu, 12 Jan 2012 00:00:10 GMT Technology collaboration - 12 ES 28G2 3NU4 OFFER

A public research organisation and a university from Spain have synthesized ceramide analogues inhibiting specifically lysosomal acid ceramidase at submicromolar levels and producing cell toxicity, growth inhibition and reduced invasiveness in human adenocarcinoma cell cultures. Since this ceramidase is overexpressed in colon, prostate and melanoma cancer, the inhibitors have potential as tumour drugs, especially if chemoresistance appears. Companies interested in a patent licence are sought.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 ES 28G2 3NU4&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=12 ES 28G2 3NU4&EnquiryType=BBS Tue, 10 Jan 2012 00:00:11 GMT Technology collaboration - 11 IL 80ER 3NO0 OFFER

An Israeli company is specializing in the production of ND (nanodiamonds) using novel proprietary technology as well as development of ND applications. The ND is state-of-the-art material widely used in polishing materials, polymers, lubricants and electrolytes. The technology is based on laser ND synthesis from soot. The company is looking for academic and industry partners engaged in cancer research and being interested in using nanodiamonds for bio-sensing and drug & gene delivery.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 IL 80ER 3NO0&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 IL 80ER 3NO0&EnquiryType=BBS Wed, 21 Dec 2011 00:00:12 GMT Technology collaboration - 11 ES 28G2 3NNS OFFER

A Spanish public research organization has devised a fast, selective capillary electrophoresis system to analyse alpha-1 acid glycoprotein (AGP or orosomucoid) isoforms. AGP purification is done in the capillary by an immunoabsorbent phase and isoforms are electrophoretically separated. The method may be useful to diagnose cancer, inflammatory or cardiovascular diseases, associated to specific AGP isoforms proportions. They look for a company interested in further development & a patent licence.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 ES 28G2 3NNS&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 ES 28G2 3NNS&EnquiryType=BBS Thu, 15 Dec 2011 00:00:13 GMT Technology collaboration - 11 RU 86FG 3NJD OFFER

A consortium of two research companies based in Tomsk developed a tumor growth inhibition model by nanosecond pulse-periodic discharge of low dose X-rays. This model disables tumor growth with 100-1000 times lower dose rates than used in conventional radiotherapy. The authors seek partners for technical cooperation and large-scale pre-clinical and clinical trials.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 RU 86FG 3NJD&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 RU 86FG 3NJD&EnquiryType=BBS Mon, 12 Dec 2011 00:00:14 GMT Technology collaboration - 11 FR 33j6 3NII OFFER

A French academic research laboratory has patented a new predictive and prognostic breast cancer biomarker. This new tool will help doctors to choose the right treatment. Industrial partners for licence agreement are sought.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 FR 33j6 3NII&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 FR 33j6 3NII&EnquiryType=BBS Fri, 25 Nov 2011 00:00:15 GMT Research partner request - 11 IL 80EP 3NDX REQUEST

The Israeli company is a cancer diagnostics company focused on breast and colorectal cancer developing a pipeline of proprietary products for screening and diagnosis of cancer. The company has exclusive IP protecting its biomarkers for early detection, prognosis and monitoring of cancer and for companion diagnostics. We offer to co-develop a biomarker based blood test for early detection of colorectal cancer (CRC) based on multiple molecules (RNA) biomarker panel.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 IL 80EP 3NDX&EnquiryType=FP7 http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 IL 80EP 3NDX&EnquiryType=FP7 Wed, 23 Nov 2011 00:00:16 GMT Technology collaboration - 11 DE 0855 3NCO OFFER

A German university offers access to monoclonal antibodies for the detection of A1/B-domains of the cancer-implicated adhesion-receptor-molecule CEACAM1. This will contribute to improve cancer research and diagnosis. Partners from academic and industrial pharmaceutical research are sought for technical co-operation.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 DE 0855 3NCO&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 DE 0855 3NCO&EnquiryType=BBS Mon, 14 Nov 2011 00:00:17 GMT Technology collaboration - 11 AT 012L 3NA3 OFFER

An Austrian core facility is offered to SME and spin-offs that develop novel therapeutic approaches for prostate cancer and seek to outsource in vitro/in vivo verification to an academic institute. Services include testing of approaches in cell culture models mimicking the different progression stages of prostate cancer and in vivo experiments using those prostate cancer cell lines for mouse xenografting. Clinical studies may be performed. They seek licence or technical cooperation partners.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 AT 012L 3NA3&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 AT 012L 3NA3&EnquiryType=BBS Mon, 7 Nov 2011 00:00:18 GMT Technology collaboration - 11 NL 60FI 3N2I OFFER

The esophageal research team of a Dutch Academic Medical Centre is one of the leading research groups in the field of endoscopic detection and treatment of early (Barrett) neoplasia of the esophagus. To perform biomarker research on the valuable collection of paraffin-material, the Dutch research group is looking for a partner to perform high-throughput biomarker testing on only a small amount of paraffin-embedded material (technical co-operation).]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 NL 60FI 3N2I&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 NL 60FI 3N2I&EnquiryType=BBS Mon, 7 Nov 2011 00:00:19 GMT Technology collaboration - 11 NL 60FI 3N33 OFFER

Dutch researchers of an Academic Medical Center have developed a new therapy against melanoma based on the potent depigmentation agent monobenzone combined with other immune modifying agents and/or immunogenic adjuvants. Partners active in R&D in the field of melanoma are sought for a license agreement.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 NL 60FI 3N33&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 NL 60FI 3N33&EnquiryType=BBS Fri, 4 Nov 2011 00:00:20 GMT Research partner request - 11 IT 54V8 3N5L REQUEST

An Italian Interdepartmental Center for Industrial Research intends to present a project on the identification of compounds for the treatment of thyroid pathologies, screen small molecules using established in vitro and in vivo approaches. They are seeking industrial and academic partners with expertise in chemical synthesis, high throughput drug screening, animal toxicology and other areas pertinent to the project.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 IT 54V8 3N5L&EnquiryType=FP7 http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 IT 54V8 3N5L&EnquiryType=FP7 Thu, 3 Nov 2011 00:00:21 GMT Technology collaboration - 11 GB 41n7 3N3X OFFER

A UK startup has launched a platform technology of growth factor conjugates, for drastically increased cellular response. In-vivo-like efficacy is achieved at concentrations typically 10&100x lower. It is expected to improve existing protocols and to enable development of new differentiation pathways. Stem cell laboratories in the industry and academia are sought for commercial agreements for the already characterised conjugates. Technical and R&D collaboration is sought for developing new ones.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 GB 41n7 3N3X&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 GB 41n7 3N3X&EnquiryType=BBS Mon, 31 Oct 2011 00:00:22 GMT Technology collaboration - 11 GB 41n7 3N3C OFFER

A UK startup has launched a fully defined cell culture media for human pluripotent cells. Pluripotency is tightly controlled so that single cell passaging and confluent monolayer expansion are enabled. Already offering savings in time and money, it will be amenable to automation. Stem cell laboratories in the industry and academia are sought for commercial agreements with technical assistance.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 GB 41n7 3N3C&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 GB 41n7 3N3C&EnquiryType=BBS Tue, 25 Oct 2011 00:00:23 GMT Technology collaboration - 11 NL 60FI 3MVS OFFER

At a Dutch Academic Medical Center it was found that cancer can effectively be treated by a combination of hyperthermia and the inhibition of two enzymes: HSP90, (protecting against heat damage) and PARP-1 (a DNA repair enzyme). A licensing agreement for this therapeutic combination is sought.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 NL 60FI 3MVS&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 NL 60FI 3MVS&EnquiryType=BBS Tue, 25 Oct 2011 00:00:24 GMT Technology collaboration - 11 NL 60FI 3N0K OFFER

Scientists at a Dutch University medical center have discovered that different forms of cholestasis and primary biliary cirrhosis are correlated with the cholestasis-associated pruritus (itch) and serum autotaxin levels. As there is no satisfactory drug against various forms of pruritus, administration of an inhibitor of autotaxin could provide a better alternative to reduce itch perception. A partner active in pharma research is sought for a license agreement.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 NL 60FI 3N0K&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 NL 60FI 3N0K&EnquiryType=BBS Mon, 24 Oct 2011 00:00:25 GMT Technology collaboration - 11 DE 0855 3N05 OFFER

Researchers at a German university have discovered novel isolated nucleic acids comprising both a pederin and a psymberin gene cluster from previously inaccessible symbiotic producers. These offer a significant scientific potential for new potent antitumor therapeutics. Biotech and or pharmaceutical companies are sought for licensing agreements or research collaboration.]]> http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 DE 0855 3N05&EnquiryType=BBS http://www.enterpriseeuropeeast.org.uk/eox/rss/clickHandler.asp?mi=470&id=11 DE 0855 3N05&EnquiryType=BBS